GTX22799 Heat Shock Protein 70 (HSP70) antibody

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0.1 ml / €480.00

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Mouse anti Human, Mouse Heat Shock Protein 70 (HSP70) JG1


Product Description for Heat Shock Protein 70 (HSP70)

Mouse anti Human, Mouse Heat Shock Protein 70 (HSP70) JG1.
Presentation: Ascites
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot.

Properties for Heat Shock Protein 70 (HSP70)

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms HSP-70, HSP70-1, HSP70-2, HSP70.1, HSPA1, HSPA1A, HSPA1B, Heat Shock 70 kDa Protein 1
Presentation Ascites
Reactivity Hu, Ms
Applications ICC/IF, IP, WB
Clonality Monoclonal
Clone JG1
Host Mouse
Isotype IgG3
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Synthetic peptide: GSGSSGTGEQKEDQKEEKQ, corresponding to amino acids 615-633 of Mouse mitochondrial Hsp70.
Application ICC, IF, IP, WB
Background The HSP 70 family is a set of highly conserved proteins that are induced by a variety of biological stresses, including heat stress, in every organism in which the proteins have been examined. The human HSP 70 family members include: HSP 70, a 70 kDa protein which is strongly inducible in all organisms but which is also constitutively expressed in primate cells; HSP 72, a 72 kDa protein which is induced exclusively under stress conditions; HSC 70, or cognate protein, is a 72 kDa constitutively expressed protein which is involved in uncoating clathrin-coated vesicles; GRP 78, or BiP, is a glucose-regulated 78 kDa protein localized to the endoplasmic reticulum; and mitochondrial HSP 70 (mtHSP 70, GRP 75 or mortalin) a 75 kDa protein that is found within the mitochondria. mtHSP 70 is a mitochondrial resident protein that is involved in protein translocation into the mitochondria. Preproteins cross the mitochondrial membranes in an extended conformation. This requires unfolding of preproteins before entering translocation pores in the mitochondrial outer membrane. Preprotein unfolding is thought to be mediated by mtHSP 70 and other inner membrane proteins of the mitochondria.
Concentration raw ascites
Storage Upon receipt - Keep as concentrated solution. Aliquot and store at -20
Buffer System:
PBS with 0.05% sodium azide
Cross-reacts with Human and Mouse. Not yet tested in other species.

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