NB600-571 Heat Shock Protein 70 (HSP70) antibody

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Mouse anti Bovine, Human, Monkey Heat Shock Protein 70 (HSP70) W27

Product Description for Heat Shock Protein 70 (HSP70)

Mouse anti Bovine, Human, Monkey Heat Shock Protein 70 (HSP70) W27.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot, Flow Cytometry, Paraffin Sections.

Properties for Heat Shock Protein 70 (HSP70)

Product Category Primary Antibodies
Quantity 0.5 ml
Synonyms HSP-70, HSP70-1, HSP70-2, HSP70.1, HSPA1, HSPA1A, HSPA1B, Heat Shock 70 kDa Protein 1
Presentation Purified
Reactivity Bov, Hu, Mky
Applications F, ICC/IF, IP, P, WB
Clonality Monoclonal
Clone W27
Host Mouse
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

HSP70 protein from HeLa cells.
Isotype control AM03096PU-N
Application flow cytometry / FACS analysis , immunohistochemistry , immunofluorescence , immunoprecipitation , Western Blot
Background Heat shock proteins (HSP's) or stress response proteins (SRP's) are synthesized in variety of environmental and pathophysiological stressful conditions. Many HSP's are involved in processes such as protein denaturation-renaturation, folding-unfolding, transport-translocation, activation-inactivation, and secretion. HSP70 is found to be associated with steroid receptors,actin, p53, polyoma T antigen, nucleotides, and other unknown proteins. Also, HSP70 has been shown to be involved in protective roles against thermal stress, cytotoxic drugs, and other damaging conditions.
Concentration 0.2 mg/ml
General Readings Welch WJ & Suhan JP. Cellular and biochemical events in mammalian cells during and after recovery from physiological stress. J Cell Biol 103:2035-52 (1986). PubMed PMID: 3536957
Welch WJ & Feramisco JR. Rapid purification of mammalian 70,000-dalton stress proteins: affinity of the proteins for nucleotides. Mol Cell Biol 5:1229-37 (1985). PubMed PMID: 4033650
Storage Store at 4C. Do not freeze.
protein A purified
Buffer System:
10mM PBS [pH7.4] with 0.2%BSA
protein A purified
Cross-reacts with Human, Cow and Monkey. Not yet tested in other species.

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