GTX15636 Hematopoiesis related Macrophage [ER-HR3] antibody

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0.25 mg / €410.00

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Rat anti Mouse Hematopoiesis related Macrophage [ER-HR3] ER-HR3


Product Description for Hematopoiesis related Macrophage [ER-HR3]

Rat anti Mouse Hematopoiesis related Macrophage [ER-HR3] ER-HR3.
Presentation: Purified
Product is tested for Frozen Sections, Flow Cytometry, Paraffin Sections.

Properties for Hematopoiesis related Macrophage [ER-HR3]

Product Category Primary Antibodies
Quantity 0.25 mg
Presentation Purified
Reactivity Ms
Applications C, F, P
Clonality Monoclonal
Clone ER-HR3
Host Rat
Isotype IgG2c
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Adherent bone marrow cells.
Application FACS, IHC-Fr, IHC-P
Background Macrophage are any of the many forms of mononuclear phagocytes found in tissues. Mononuclear phagocytes arise from hematopoietic stem cells in the bone marrow. After passing through the monoblast and promonocyte states of the monocyte stage, they enter the blood, circulating for about 40 hours. They then enter tissues and increase in size, phagocytic activity, and lysosomal enzyme content and become macrophages. The morphology of macrophages varies among different tissues and between normal and pathologic states, and not all macrophages can be identified by morphology alone. However, most macrophages are large cells with a round or indented nucleus, a well developed Golgi apparatus, abundant endocytotic vacuoles, lysosomes, and phagolysosomes, and a plasma membrane covered with ruffles or microvilli. Among the functions of macrophages are nonspecific phagocytosis and pinocytosis, specific phagocytosis of opsonized microorganisms mediated by Fc receptors and complement receptors, killing of ingested microorganisms, digestion and presentation of antigens to T and B lymphocytes, and secretion of a large number of diverse products, including many enzymes (lysozyme, collagenases, elastase, acid hydrolases), several complement components and coagulation factors, some prostaglandins and leukotrienes, and several regulatory molecules (interferon, interleukin 1). Among the cells now recognized as macrophages are histiocytes, Kupffer cells, osteoclasts, microglial cells, synovial type A cells, interdigitating cells, and Langerhans cells (in normal tissues) and epithelioid cells and Langerhans type and foreign body type multinucleated giant cells (in inflamed tissues).
Concentration 1 mg/ml
Storage Keep as concentrated solution. Store at 4
Protein G purified
Buffer System:
Preservative: 0.01% Thimerosal Constituents: PBS, 10mg/ml BSA. pH 7.2
Protein G purified
Cross-reacts with Mouse. Not yet tested in other species.

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