AM01144PU-N Heparin / Heparan Sulfate antibody

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0.1 mg / €490.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human, Mammalia Heparin / Heparan Sulfate T320.11


Product Description for Heparin / Heparan Sulfate

Mouse anti Human, Mammalia Heparin / Heparan Sulfate T320.11.
Presentation: Purified
Product is tested for Radioimmunoassay, Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Heparin / Heparan Sulfate

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu, Mam
Applications E, R, WB
Clonality Monoclonal
Clone T320.11
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Application ELISA (1-10 μg/ml).
(1-10 μg/ml).
Background Heparan sulfate is a sulfated polysaccharide that is found on the surface of most cells as part of proteoglycans. Heparan sulfate is also present in the extracellular matrix. The polysaccharide mediates the interactions between a number of different proteins.
Both heparin and heparan sulfate are composed of alternating sequences of glucosamine and uronic acid with heparin being the more heavily sulfated polymer (Gallagher & Walker, 1985).
Concentration 1.0 mg/ml
General Readings
  1. Shibata S, Harpel P, Bona C, Fillit H. Monoclonal antibodies to heparan sulfate inhibit the formation of thrombin-antithrombin III complexes. Clin Immunol Immunopathol. 1993 Jun;67(3 Pt 1):264-72. PubMed PMID: 8500274.
  2. Coles CH, Shen Y, Tenney AP, Siebold C, Sutton GC, Lu W, et al. Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension. Science. 2011 Apr 22;332(6028):484-8. doi: 10.1126/science.1200840. Epub 2011 Mar 31. PubMed PMID: 21454754. (Free PMC Article available, 4 images available)
  3. Gallagher JT, Walker A. Molecular distinctions between heparan sulphate and heparin. Analysis of sulphation patterns indicates that heparan sulphate and heparin are separate families of N-sulphated polysaccharides. Biochem J. 1985 Sep 15;230(3):665-74. PubMed PMID: 2933029. (Free PMC Article available)
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Affinity Chromatography on Protein A
Buffer System:
0.09% Sodium Azide
Liquid purified IgG fraction
This antibody clone T320.11 recognizes the chemically related αβ-linked glycosaminoglycans Heparin and Heparan sulfate.
Human, Mammals.

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