discontinued

bs-1557G Hepatitis B Surface Antigen / HBsAg antibody

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0.1 ml / €240.00

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Goat anti Human Hepatitis B Surface Antigen / HBsAg

bs-1557G

Product Description for Hepatitis B Surface Antigen / HBsAg

Goat anti Human Hepatitis B Surface Antigen / HBsAg.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for Hepatitis B Surface Antigen / HBsAg

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms HBV surface antigen, Hepatitis B Virus
Presentation Purified
Reactivity Hu
Applications P, WB
Clonality Polyclonal
Host Goat
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

Immunogen
Immunogen:
Human Hepatitis B Surface Antigen.
Background Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
Product Citations
Originator or purchased from resellers:
  1. Watanabe, Tsunamasa, et al. "Post-Exposure Prophylactic Effect of HBV-active Antiretroviral Therapy Against Hepatitis B Virus Infection." Antimicrobial Agents and Chemotherapy (2014): AAC-04459.
  2. Ma, Yan-Xiu, et al. "Successful establishment and evaluation of a new animal model for studying the hepatitis B virus YVDD mutant." Archives of virology (2012): 1-7.
Storage Store at -20°C for 12 months.
Format
Purification:
Purified by Protein A and peptide affinity chromatography.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
State:
Purified

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