DM343P Heregulin (NDF, GGF, Neuregulin) antibody

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Mouse anti Human, Mouse, Rat Heregulin (NDF, GGF, Neuregulin) 7D5


Product Description for Heregulin (NDF, GGF, Neuregulin)

Mouse anti Human, Mouse, Rat Heregulin (NDF, GGF, Neuregulin) 7D5.
Presentation: Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for Heregulin (NDF, GGF, Neuregulin)

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Monoclonal
Clone 7D5
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Biomeda

Datasheet Extract

Recombinant extracellular domain of rat NDF protein.
Isotype control AM03096PU-N
Application Immunoprecipitation (2µg/mg protein lysate, use Protein A). Western blotting (1-2 µg/ml for 2hrs at RT). Immunohistology (Formalin/paraffin: 1-2 µg/ml for 30 min at RT. Staining of formalin/paraffin tissues REQUIRES boiling tissue sections in 10mM citrate buffer, pH 6.0. Recommended positive control: Prostate Carcinoma). Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Concentration 0.2 mg/ml
General Readings 1 Lupu, R., et al. (1995) Seminars in Cancer Biology, 6:135-145.
2 Holmes W, et al. (1992)Scien
Storage Store the antibody at 4°C. Do not freeze! Shelf life: one year from despatch.
Heregulin (HRG) or Neu Differentiation Factor (NDF) binds to c-erbB-3 and cerbB-4 receptors on mammary and neuronal cells with low and high affinities, respectively. HRG/NDF exists in several isoforms, which are classified in two groups, a and b, that differ in their EGF-like domain and in receptor binding affinity. Reacts with Human, Rat, and Mouse. Others not tested. Cellular Localization: cytoplasmic, Intercellular Spaces.

Mol. Wt of Antigen: 44kD

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