AM09074PU-N Herpes Virus Type 8 / HHV8 ORF73 (122-329) antibody

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0.1 ml / €310.00
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Mouse anti Human Herpes Virus Type 8 / HHV8 AT4C11

AM09074PU-N

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  • AM09074PU-N

Product Description for Herpes Virus Type 8 / HHV8

Mouse anti Human Herpes Virus Type 8 / HHV8 AT4C11.
Properties: ORF73 (122-329)
Presentation: Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for Herpes Virus Type 8 / HHV8

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms HHV-8, Human herpesvirus 8 type P ORF73 protein, Kaposi's sarcoma-associated herpesvirus encoded protein ORF73, LANA-1, LNA, LNA1, ORF-73
Presentation Purified
Reactivity Hu
Applications E, P, WB
Clonality Monoclonal
Clone AT4C11
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9QR71
Immunogen:
Recombinant Human ORF73/HHV8 (122-329 aa) purified from E. coli
GeneID:
4961527
Property 122-329, ORF73
Isotype control AM03096PU-N
Application ELISA.
Western blot (1/1000-1/2000).
Immunohistochemistry on Paraffin Embedded Sections (1/50-1/100).
Background ORF73 protein of human herpesvirus 8 (HHV-8) is a Kaposi's sarcoma-associated herpesvirus (KSHV) latent protein which has been suspected of playing a crucial role in modulating viral and cellular gene expression. ORF73 is associated with cellular chromatin and stays on the chromosomes during cell division. It maintains the viral genomes during cell division by tethering the viral episomes to the chromosomes. It binds directly to replication origin recognition complexes (ORCs) that are primarily associated with the terminal repeat (TR) region of the HHV-8 genome.
Concentration 1.0 mg/ml
General Readings
  1. Kedes D.H., et al. (1997) Journal of Clinical Investigation. 100: 2610–2606.
  2. Verma SC, Lan K, Choudhuri T, Robertson ES. Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen modulates K1 expression through its cis-acting elements within the terminal repeats. J Virol. 2006 Apr;80(7):3445-58. PubMed PMID: 16537612. (Free PMC Article available, 10 images available)
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Buffer System:
PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State:
Liquid purified Ig fraction
Purified
Specificity
Specificity:
The antibody recognizes the ORF73 protein of Human herpesvirus 8 (HHV-8).
Other species not tested.
Gene ID 4961527

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