AP07000SU-N Herpes Virus Type 8 / HHV8 ORF8 antibody

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Rabbit anti Human Herpes Virus Type 8 / HHV8

Product Description for Herpes Virus Type 8 / HHV8

Rabbit anti Human Herpes Virus Type 8 / HHV8.
Properties: ORF8
Presentation: Serum
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Herpes Virus Type 8 / HHV8

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms KSHV ORF8
Presentation Serum
Reactivity Hu
Applications E, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8.
Property ORF8
Application Western Bloting: 1/500 - 1/2000.
ELISA: 1/10000.
Background Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.
General Readings
  1. James J. Proc. Natl. Acad. Sci Vol. 1993, pp. 14862-14867.
  2. Wang FZ, Akula SM, Sharma-Walia N, Zeng L, Chandran B. Human herpesvirus 8 envelope glycoprotein B mediates cell adhesion via its RGD sequence. J Virol. 2003 Mar;77(5):3131-47. PubMed PMID: 12584338. (Free PMC Article available, 10 images available)

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Rabbit anti-serum.
Species Reactivity
Species reactivity (tested):
This antibody reacts to KSHV ORF8.
Gene ID 4961501

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