TA501147 HIF1 beta / ARNT antibody

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Search for all "HIF1 beta / ARNT"

0.1 ml / €379.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti Human HIF1 beta / ARNT OTI1A1

TA501147

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Product Description for HIF1 beta / ARNT

Mouse anti Human HIF1 beta / ARNT OTI1A1.
Presentation: Purified
Product is tested for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Properties for HIF1 beta / ARNT

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms Aryl hydrocarbon receptor nuclear translocator, BHLHE2, Class E basic helix-loop-helix protein 2, Dioxin receptor, HIF-1 beta, Hypoxia-inducible factor 1 beta
Presentation Purified
Reactivity Hu
Applications F, ICC/IF, P, WB
Clonality Monoclonal
Clone OTI1A1
Host Mouse
Isotype IgG1
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P27540
Immunogen:
Full length human recombinant protein of human ARNT (NP_001659) produced in HEK293T cell.
GeneID:
405
Isotype control AM03095PU-N, SM10P (for use in human samples)
Application WB 1:2000
IHC 1:50
IF 1:100
FLOW 1:100
Background The aryl hydrocarbon (Ah) receptor is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free, cytosolic form of the Ah receptor is complexed to heat shock protein 90. Binding of ligand, which includes dioxin and polycyclic aromatic hydrocarbons, results in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a complex with the ligand-bound Ah receptor, and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor, hypoxia-inducible factor 1 (HIF1). A t(1;12)(q21;p13) translocation, which results in a TEL-ARNT fusion protein, is associated with acute myeloblastic leukemia. Three altertively spliced variants encoding different isoforms have been described for this gene.
Product Citations
Originator or purchased from resellers:
  1. Hao N, Bhakti VL, Peet DJ, Whitelaw ML. Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiation. Nucleic Acids Res. 2013 Jun;41(11):5626-38. doi: 10.1093/nar/gkt206. Epub 2013 Apr 17. PubMed PMID: 23599003. (Free PMC Article available, 7 images available)
Format
Purification:
Purified from mouse ascites fluids by affinity chromatography
Buffer System:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for HIF1 beta / ARNT (5 products)

Catalog No. Species Pres. Purity   Source  

HIF1 beta / ARNT (transcript variant 1)

HIF1 beta / ARNT Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

HIF1 beta / ARNT

HIF1 beta / ARNT Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

HIF1 beta / ARNT

HIF1 beta / ARNT Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

HIF1 beta / ARNT

HIF1 beta / ARNT Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

HIF1 beta / ARNT

HIF1 beta / ARNT Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Positive controls for HIF1 beta / ARNT (3 products)

Catalog No. Species Pres. Purity   Source  

ARNT overexpression lysate

ARNT overexpression lysate
0.1 mg / €480.00
  OriGene Technologies, Inc.

HIF1 beta / ARNT Lysate(Denatured)

HIF1 beta / ARNT Lysate(Denatured)
0.1 ml / €270.00
  Abnova Taiwan Corp.

HIF-1 beta Lysate

Western Blot: HIF-1 beta Lysate [NBL1-07720] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for ARNT Protein
0.1 mg / €620.00
  Novus Biologicals Inc.
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