NB100-132 HIF2A / HIF2 alpha antibody

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0.1 ml / €330.00
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Mouse anti Human, Rat HIF2A / HIF2 alpha ep190b

NB100-132

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  • NB100-132

Product Description for HIF2A / HIF2 alpha

Mouse anti Human, Rat HIF2A / HIF2 alpha ep190b.
Presentation: Purified
Product is tested for Western blot / Immunoblot, Flow Cytometry, Paraffin Sections.

Properties for HIF2A / HIF2 alpha

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms BHLHE73, Basic-helix-loop-helix-PAS protein MOP2, Class E basic helix-loop-helix protein 73, EPAS1, Endothelial PAS domain-containing protein 1, HIF-1 alpha-like factor, HIF-2 alpha, HIF-related factor, HLF, Hypoxia-inducible factor 2 alpha, MOP2, PASD2
Presentation Purified
Reactivity Hu, Rt
Applications F, P, WB
Clonality Monoclonal
Clone ep190b
Host Mouse
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q99814
Immunogen:
Human HIF-2 alpha amino acids 535-631.
GeneID:
2034
Add. information Research Areas: Cancer, Hypoxia
Application flow cytometry / FACS analysis, Immunohistochemistry-Paraffin, Western Blot, Western Blot (recognizes a band at ~118 kDa representing HIF-2 alpha) Immunohistochemistry: Has been used on paraffin-embedded sections an approximate 1:150-1:300 range, flow cytometry / FACS analysis 1.0 ug, Western Blot 1:500, Immunohistochemistry-Paraffin 1:150-1:300,
Background Hypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. HIF-2 alpha is predominantly expressed in highly vascularized tissues of adult humans and endothelial cells of the embryonic and adult mouse, whereas HIF-1 alpha functions primarily in extravascular tissues. HIF-2 alpha is also a potent activator of the tie-2 gene, which is known to be selectively expressed in endothelial cells.
Concentration 1.6 mg/ml
General Readings
  1. Wiesener MS, Turley H, Allen WE, Willam C, Eckardt KU, Talks KL, et al. Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha. Blood. 1998 Oct 1;92(7):2260-8. PubMed PMID: 9746763.
Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Format
Purification:
protein G purified
Buffer System:
0.1% Sodium Azide
Purity:
protein G purified
State:
Purified
Specificity
Specificity:
This is specific for HIF-2 alpha and does not cross-react with HIF-1 alpha.
Species:
Human, Mouse, Rat
Gene ID 2034

Accessory Products

Proteins and/or Positive Controls

Proteins for HIF2A / HIF2 alpha (8 products)

Catalog No. Species Pres. Purity   Source  

HIF2A / HIF2 alpha (panel)

HIF2A / HIF2 alpha
1 kit / €410.00
  GeneTex Inc.

HIF2A / HIF2 alpha

HIF2A / HIF2 alpha Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

HIF2A / HIF2 alpha

HIF2A / HIF2 alpha Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

HIF2A / HIF2 alpha

HIF2A / HIF2 alpha Human
2 µg / €300.00
  Abnova Taiwan Corp.

HIF2A / HIF2 alpha

HIF2A / HIF2 alpha Human 12.5% SDS-PAGE Stained with Coomassie Blue
10 µg / €380.00
  Abnova Taiwan Corp.

HIF2A / HIF2 alpha

HIF2A / HIF2 alpha Human 12.5% SDS-PAGE Stained with Coomassie Blue
25 µg / €510.00
  Abnova Taiwan Corp.

HIF2A / HIF2 alpha

HIF2A / HIF2 alpha Human 12.5% SDS-PAGE Stained with Coomassie Blue
10 µg / €380.00
  Abnova Taiwan Corp.

HIF2A / HIF2 alpha

HIF2A / HIF2 alpha Human 12.5% SDS-PAGE Stained with Coomassie Blue
25 µg / €510.00
  Abnova Taiwan Corp.

Positive controls for HIF2A / HIF2 alpha (2 products)

Catalog No. Species Pres. Purity   Source  

EPAS1 293T Cell Transient Overexpression Lysate(Denatured)

EPAS1 293T Cell Transient Overexpression Lysate(Denatured)
0.1 ml / €270.00
  Abnova Taiwan Corp.

HIF-2 alpha Lysate

Western Blot: HIF-2 alpha Lysate [NBL1-10286] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for EPAS1
0.1 mg / €400.00
  Novus Biologicals Inc.
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