AM50638PU-S HINT2 antibody

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50 µl / €220.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human HINT2 AT5B10

Product Description for HINT2

Mouse anti Human HINT2 AT5B10.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Flow Cytometry, Western blot / Immunoblot.

Properties for HINT2

Product Category Primary Antibodies
Target Category
Quantity 50 µl
Synonyms HINT-2, HINT-3, HIT-17kDa, Histidine triad nucleotide-binding protein 2, PKCI-1-related HIT protein
Presentation Purified
Reactivity Hu
Applications E, F, WB
Clonality Monoclonal
Clone AT5B10
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9BX68
Immunogen:
Recombinant human HINT2 (18-163aa) purified from E. coli.
Isotype control AM03095PU-N, SM10P (for use in human samples)
Application The antibody has been tested by ELISA, Western blot analysis and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Background Histidine triad nucleotide binding protein 2 (HINT2) is a mitochondrial protein. This protein is an AMP-lysine hydrolase and phosphoamidase and may contribute to tumor suppression. This protein is a member of the HIT superfamily and Hint subfamily, which are characterized as nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides. HINT2 regulates steroidogenesis through calcium-dependent and calcium-independent siglling pathways that may serve to maintain a favorable mitochondrial potential. Its role in calcium homeostasis may also contribute to its proapoptotic function in hepatocytes and other non-steroidogenic cells, though the exact mechanism remains unclear.
Concentration 1.0 mg/ml
General Readings Maize KM., et al. (2013) The FEBS journal. 280(14): 3389-3398.Lenglet S., et al. (2008) Endocrinology. 149(11): 5461-5469.Martin J., et al. (2006) Gastroenterology. 130(7): 2179-2188.Lee LR., et al. (2013) Cancer prevention research. 6(7): 731-743.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein-A affinity chromatography
Buffer System:
Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
State:
Liquid purified Ig fraction
Purified
Specificity
Species:
Human.

Accessory Products

Proteins and/or Positive Controls

Proteins for HINT2 (7 products)

Catalog No. Species Pres. Purity   Source  

HINT2

HINT2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

HINT2 (18-163, His-tag)

HINT2 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €730.00
  Acris Antibodies GmbH

HINT2 (18-163, His-tag)

HINT2 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €300.00
  Acris Antibodies GmbH

HINT2

HINT2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

HINT2

HINT2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

HINT2

HINT2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

HINT2

HINT2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for HINT2 (2 products)

Catalog No. Species Pres. Purity   Source  

HINT2 Lysate

Western Blot: HINT2 Lysate [NBL1-11546] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for HINT2
  Novus Biologicals Inc.

HINT2 overexpression lysate

HINT2 overexpression lysate
0.1 mg / €280.00
  OriGene Technologies, Inc.
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