NB100-745 Histone Core antibody

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Sheep anti Bovine, Mouse Histone Core


Product Description for Histone Core

Sheep anti Bovine, Mouse Histone Core.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Immunoprecipitation, Western blot / Immunoblot.

Properties for Histone Core

Product Category Primary Antibodies
Quantity 0.125 mg
Presentation Purified
Reactivity Bov, Ms
Applications E, IP, WB
Clonality Polyclonal
Host Sheep
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Intact calf H-3 complexed to rRNA.
Add. information Research Areas: DNA Repair
Application ELISA, immunofluorescence, immunoprecipitation, Western Blot, Immunofluorescence. Immunoprecipitaion. Western Blot. Enzyme-linked immunosorbent assay, ELISA, immunofluorescence, immunoprecipitation, Western Blot
Background In diploid eukaryotic cells, the chromatin fibers are about 20nM in diameter. They consist of two major components in equal amounts, DNA and basic proteins called histones. Histones are believed to be regularly arranged in the deep grove of the DNA helix. The recurring positive charges of the histones form electrostatic associations with the negatively charged phosphate groups of DNA making the DNA more stable and flexible. This allows for the supercoiling of the chromatin fibers. The histone core protein is an octamer consisting of 2 subunits of each of histone 2A, 2B, 3 and 4. In conjunction with the linker histone H1 and the nonhistone chromosomal proteins, it is responsible for the binding and compacting of DNA into chromatin. The sequences of the core histones are highly conserved from species to species.
Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
protein G purified
Buffer System:
0.1% Sodium Azide
protein G purified
This is specific for Histone-Core.

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