discontinued

bs-3769R Histone H3.1 (Dimethyl K36) antibody

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0.1 ml / €250.00

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Rabbit anti Human, Mouse, Rat Histone H3.1

bs-3769R

Product Description for Histone H3.1

Rabbit anti Human, Mouse, Rat Histone H3.1.
Properties: (Dimethyl K36)
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for Histone H3.1

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms H3/a, H3/b, H3/c, H3/d, H3/f, H3/h, H3/i, H3/j, H3/k, H3/l, H3FA, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J
Presentation Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

Immunogen
Immunogen:
KLH conjugated synthetic metylpeptide derived from human Histone H3 around metylation site of Di Methyl Lys36.
Property Dimethyl K36
Application WB(1:100-1000)
IHC-P(1:100-500)
IF(IHC-P)(1:50-200)
Background Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
Storage Store at -20°C for 12 months.
Format
Purification:
Purified by Protein A.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
State:
Purified

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