AM33314PU-N HIV-1 Gag Capsid protein p24 antibody

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0.2 mg / €390.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti HIV-1 HIV1-24/661

AM33314PU-N

Product Description for HIV-1

Mouse anti HIV-1 HIV1-24/661.
Properties: Gag Capsid protein p24
Presentation: Purified
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence.

Properties for HIV-1

Product Category Primary Antibodies
Quantity 0.2 mg
Synonyms HIV-I, HIV1, Human immunodeficiency virus type 1
Presentation Purified
Applications C, ICC/IF
Clonality Monoclonal
Clone HIV1-24/661
Host Mouse
Isotype IgG1
Molecular weight 24kDa (mature); 55kDa & 41kDa (precursors)
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P04585
Immunogen:
Recombinant HIV-1 Gag p24 protein.
GeneID:
155348
Property Gag Capsid protein p24
Isotype control AM03095PU-N
Application ELISA: Use BSA free Antibody for Coating.
Immunofluorescence: 0.5-1 μg/ml.
Immunocytochemistry on Acetone or Paraformaldehyde Fixed Sections: 0.5-1.0 μg/ml for 30 minutes at RT.
Positive Control: HIV-1 infected cells or tissues.
Background Human Immunodeficiency Virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.
Concentration 0.2 mg/ml
General Readings
  1. Voltersvik P, Bostad L, Dyrhol-Riise AM, Eide GE, Røsok BI, Olofsson J, et al. Cystatin A and HIV-1 p24 antigen expression in tonsillar lymphoid follicles during HIV-1 infection and during highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2006 Mar;41(3):277-84. PubMed PMID: 16540928.
Storage Store undiluted at 2-8°C.
Shelf life: one year from despatch.
Format
Purification:
Protein A/G Chromatography
Buffer System:
10mM PBS
Preservatives:
0.05% Sodium Azide
Stabilizers:
0.05% BSA
State:
Liquid purified IgG fraction from Bioreactor Concentrate
Purified
Specificity
Specificity:
Recognizes Human Immunodeficiency Virus Type-1 p24(HIV1-p24).
Cellular Localization: Membrane.

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