NB100-64162 HLA Class II DP, DR, DQ antibody

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0.1 mg / €360.00
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Mouse anti Human HLA Class II DP, DR, DQ Bu26

NB100-64162

Product Description for HLA Class II DP, DR, DQ

Mouse anti Human HLA Class II DP, DR, DQ Bu26.
Presentation: Aff - Purified
Product is tested for Flow Cytometry.

Properties for HLA Class II DP, DR, DQ

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms DQ, DR, HLA class II histocompatibility antigen DP, HLA-DP, HLA-DQ, HLA-DR, MHC class II antigen DP
Presentation Aff - Purified
Reactivity Hu
Applications F
Clonality Monoclonal
Clone Bu26
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Made to Human HLA DP DQ DR
Add. information Research Areas: Immunology
Application flow cytometry / FACS analysis, Flow cytometry / FACS analysis, flow cytometry / FACS analysis 1:100 - 1:200
Background The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates containing many genes with important immune system roles. In humans, the MHC spans almost 4 megabases of chromosome 6 and includes more than 200 known genes, of which about half have known immmunological functions. The best known genes in the MHC region are the subset that encodes cell-surface antigen-presenting proteins. In humans, these genes are referred to as human leukocyte antigen (HLA) genes. The most intensely studied HLA genes are: HLA A, HLA B, HLA C, HLA DPA, HLA DPB1, HLA DQA1, HLA DQB1, HLA DRA, and HLA DRB1. In humans, the HLA is divided into three regions: Class I, II, and III. The A, B, and C genes belong to HLA class I while the six D genes belong to class II.
Concentration 1 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
protein G purified
Buffer System:
0.09% Sodium Azide
Purity:
protein G purified
State:
Aff - Purified
Specificity
Specificity:
NB100-64162 recognizes the beta chains of class II human major histocompatibility (MHC) antigens. The antibody reacts with DP, DQ, DR beta chains, which are expressed by antigen presenting cells, B- cells, monocytes and activated T lymphocytes. MHC class II molecules play a central role in the immune system by presenting peptides derived from extracellular proteins.
Species:
Human

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