NB120-17101 HLA Class II DP, DR, DQ antibody

See related secondary antibodies

Search for all "HLA Class II DP, DR, DQ"

Quick Overview

Mouse anti Human HLA Class II DP, DR, DQ CR3/43


Product Description for HLA Class II DP, DR, DQ

Mouse anti Human HLA Class II DP, DR, DQ CR3/43.
Product is tested for Paraffin Sections.

Properties for HLA Class II DP, DR, DQ

Product Category Primary Antibodies
Quantity 1 ml
Synonyms DQ, DR, HLA class II histocompatibility antigen DP, HLA-DP, HLA-DQ, HLA-DR, MHC class II antigen DP
Reactivity Hu
Applications P
Clonality Monoclonal
Clone CR3/43
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Unfortunately, this information is considered to be commercially sensitive
Add. information Research Areas: Lipid and Metabolism, Immunology
Application Immunohistochemistry-Paraffin, IHC-P: 1/25 - 1/50, in an ABC method.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user., Immunohistochemistry-Paraffin
Background The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates containing many genes with important immune system roles. In humans, the MHC spans almost 4 megabases of chromosome 6 and includes more than 200 known genes, of which about half have known immmunological functions. The best known genes in the MHC region are the subset that encodes cell-surface antigen-presenting proteins. In humans, these genes are referred to as human leukocyte antigen (HLA) genes. The most intensely studied HLA genes are: HLA A, HLA B, HLA C, HLA DPA, HLA DPB1, HLA DQA1, HLA DQB1, HLA DRA, and HLA DRB1. In humans, the HLA is divided into three regions: Class I, II, and III. The A, B, and C genes belong to HLA class I while the six D genes belong to class II.
General Readings General / background references:Zaloudik J et al. DNA content and MHC class II antigen expression in malignant melanoma: clinical course. J Clin Pathol 41:1078-84 (1988). PubMed PMID: 3192729
Smith ME et al. Major histocompatibility complex class II antigen expression in B and T cell non-Hodgkin's lymphoma. J Clin Pathol 40:34-41 (1987). PubMed PMID: 3546388
Stein H et al. Immunohistological analysis of human lymphoma: correlation of histological and immunological categories. Adv Cancer Res 42:67-147 (1984). PubMed PMID: 6395656
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Tissue culture supernatant
Buffer System:
Sodium Azide
Tissue culture supernatant
This antibody reacts with the beta chain of all products of the gene sub regions DP, DQ, and DR. It stains B cells, interdigitating reticulum cells, Langerhans cells and many macrophages. This does not react with normal T cell and polymorphs but stains activated T cells.

Accessory Products

  • LinkedIn