NB600-1255 HLA Class II DP, DR, DQ antibody

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Mouse anti Human HLA Class II DP, DR, DQ


Product Description for HLA Class II DP, DR, DQ

Mouse anti Human HLA Class II DP, DR, DQ
Product is tested for Immunocytochemistry/Immunofluorescence.

Properties for HLA Class II DP, DR, DQ

Product Category Primary Antibodies
Quantity 0.5 ml
Synonyms DQ, DR, HLA class II histocompatibility antigen DP, HLA-DP, HLA-DQ, HLA-DR, MHC class II antigen DP
Reactivity Hu
Applications ICC/IF
Clonality Monoclonal
Host Mouse
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Application immunofluorescence, For use in regular immunofluorescence and microcytotoxicity methods, dilution 1:5, preferably in PBS plus 1% BSA and 0.01% sodium azide is advised. , immunofluorescence 1:5
Background The antibody is useful for the identification of HLA-D positive molecules using either microcytotoxicity testing or immunofluorescence/immunoperoxidase procedures. Furthermore, it was found useful for studies on functional aspects of MHC class II molecules.
General Readings General / background references:Doveren RF et al. Canine MHC-class II antigens on B and T lymphocytes. Tissue Antigens 27:87-98 (1986). PubMed PMID: 3518148
Koning F et al. A monoclonal antibody detecting an HLA-DQwl-related determinant. Tissue Antigens 26:100-9 (1985). PubMed PMID: 2414859
Koning F et al. A mouse monoclonal antibody detecting a DR-related MT2-like specificity: serology and biochemistry. Hum Immunol 9:221-30 (1984). PubMed PMID: 6232245
Storage Store at 4C. Do not freeze.
Buffer System:
0.01% Sodium Azide
The reacts with a monomorphic determinant on MHC class II HLA-D region molecules. It detects the molecules of the HLA-DR, DP and DQ loci. It inhibits the mixed lymphocyte culture. It also reacts with MHC class II molecules of various animals.

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