NBP1-22549 HLA Class II DP, DR, DQ antibody

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0.5 ml / €400.00
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Mouse anti Human HLA Class II DP, DR, DQ CR3/43

NBP1-22549

Product Description for HLA Class II DP, DR, DQ

Mouse anti Human HLA Class II DP, DR, DQ CR3/43.
Presentation: Supernatant
Product is tested for Paraffin Sections.

Properties for HLA Class II DP, DR, DQ

Product Category Primary Antibodies
Quantity 0.5 ml
Synonyms DQ, DR, HLA class II histocompatibility antigen DP, HLA-DP, HLA-DQ, HLA-DR, MHC class II antigen DP
Presentation Supernatant
Reactivity Hu
Applications P
Clonality Monoclonal
Clone CR3/43
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Tonsil cells
Add. information Research Areas: Immunology
Application immunohistochemistry, ABC, immunohistochemistry 1:25-1:50
Background The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates containing many genes with important immune system roles. In humans, the MHC spans almost 4 megabases of chromosome 6 and includes more than 200 known genes, of which about half have known immmunological functions. The best known genes in the MHC region are the subset that encodes cell-surface antigen-presenting proteins. In humans, these genes are referred to as human leukocyte antigen (HLA) genes. The most intensely studied HLA genes are: HLA A, HLA B, HLA C, HLA DPA, HLA DPB1, HLA DQA1, HLA DQB1, HLA DRA, and HLA DRB1. In humans, the HLA is divided into three regions: Class I, II, and III. The A, B, and C genes belong to HLA class I while the six D genes belong to class II. This antibody principally labels B cells, interdigitating reticulum cells, Langerhans
Storage Store at 4C. Do not freeze.
Format
Purification:
Tissue culture supernatant
Buffer System:
Sodium Azide
Purity:
Tissue culture supernatant
State:
Supernatant
Specificity
Specificity:
This antibody reacts with the beta chain of all products of the gene sub regions DP, DQ, and DR. It stains B cells, interdigitating reticulum cells, Langerhans cells and many macrophages. This does not react with normal T cell and polymorphs but stains activated T cells.
Species:
Human

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