AM26129BT-N HLA Class II DR antibody

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0.1 mg / €310.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human HLA Class II DR EDU-1

Product Description for HLA Class II DR

Mouse anti Human HLA Class II DR EDU-1.
Presentation: Biotin
Product is tested for Frozen Sections, Flow Cytometry.

Properties for HLA Class II DR

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms HLA class II histocompatibility antigen DR, HLA-DR, MHC class II antigen DR
Presentation Biotin
Reactivity Hu
Applications C, F
Clonality Monoclonal
Clone EDU-1
Host Mouse
Isotype IgG2b
Shipping to USA/Canada
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Isotype control SM12B
Add. information Antigen distribution:
Isolated cells: Antigen presenting cells (macrophages, B-cells and dendritic cells) are the cells in which DR are typically found.
Application Immunohistochemistry on Frozen Sections: 0.1 µg/ml (1/2000).
Suggested Positive Control: Human tonsil.
Has been described to work in FACS.
Background

HLA DR antigen is an HLA class II antigen with homology to murine H-2E. HLA-DR is an αβ heterodimer. The N-terminal domain of the mature protein forms an alpha-helix that constitutes the exposed part of the binding groove, the C-terminal cytoplasmic region interacts with the other chain forming a beta-sheet under the binding groove spanning to the cell membrane.

Concentration 0.2 mg/ml (after reconstitution)
General Readings
  1. Fernandez N, Labeta MO, Festenstein H. A novel HLA class II molecule. Immunogenetics. 1988;27(5):363-9. PubMed PMID: 3258581.
  2. Arrizabalaga P, Mirapeix E, Darnell A, Torras A, Revert L. Cellular immunity analysis using monoclonal antibodies in human glomerulonephritis. Nephron. 1989;53(1):41-9. PubMed PMID: 2789343.
  3. Ong GL, Mattes MJ.: Processing of antibodies to the MHC class II antigen by B-cell lymphomas: release of Fab-like fragments into the medium. Mol Immunol. 36(11-12): 777-88 (1999).
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Label:
Biotin
Purification:
Affinity Chromatography
Buffer System:
Phosphate buffered saline pH 7.2 (PBS)
Preservatives:
0.05 % (v/v) Kathon CG
Stabilizers:
5 mg/ml BSA
State:
Lyophilized purified Ig fraction
Reconstitution:
Restore by adding 0.5ml distilled water.
Species Reactivity
Species reactivity (tested):
Human
Specificity
Specificity:
This antibody recognizes HLA DR antigen.

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