NB500-406 HLA Class II DR + DP antibody

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0.1 mg / €340.00
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Quick Overview

Mouse anti Human, Porcine HLA Class II DR + DP HL-38

NB500-406

Product Description for HLA Class II DR + DP

Mouse anti Human, Porcine HLA Class II DR + DP HL-38.
Presentation: Aff - Purified
Product is tested for Immunoprecipitation, Western blot / Immunoblot, Flow Cytometry.

Properties for HLA Class II DR + DP

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms DP, HLA class II histocompatibility antigen DR, HLA-DP, HLA-DR, MHC class II antigen DR, W4
Presentation Aff - Purified
Reactivity Hu, Por
Applications F, IP, WB
Clonality Monoclonal
Clone HL-38
Host Mouse
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Tissue / cell preparation (Human). (Burkitt lymphoma cell line Raji).
Add. information Research Areas: Lipid and Metabolism, Immunology
Application flow cytometry / FACS analysis, immunoprecipitation, Western Blot, FACS: Use at an assay dependant concentration. IP: Use at an assay dependant concentration. WB: Use at an assay dependant concentration. Use under non-reducing conditions.Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user., flow cytometry / FACS analysis, immunoprecipitation, Western Blot
Background Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
General Readings This product has been used in:Horejsi
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Affinity purified
Buffer System:
15mM Sodium Azide
Purity:
Affinity purified
State:
Aff - Purified
Specificity
Specificity:
This antibody binds to a common epitope on the b-chain of human HLA-DR and HLA-DP., The also reacts with porcine MHC class II antigens (SLA-D gene products).
Species:
Human

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