NB500-407 HLA Class II DR + DP antibody

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100 Tests / €360.00
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Quick Overview

Mouse anti Human, Porcine HLA Class II DR + DP HL-38

NB500-407

Product Description for HLA Class II DR + DP

Mouse anti Human, Porcine HLA Class II DR + DP HL-38.
Presentation: FITC
Product is tested for Flow Cytometry, Immunoprecipitation, Western blot / Immunoblot.

Properties for HLA Class II DR + DP

Product Category Primary Antibodies
Quantity 100 Tests
Synonyms DP, HLA class II histocompatibility antigen DR, HLA-DP, HLA-DR, MHC class II antigen DR
Presentation FITC
Reactivity Hu, Por
Applications F, IP, WB
Clonality Monoclonal
Clone HL-38
Host Mouse
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Burkitts lymphoma cell line Raji (Human).
Add. information Research Areas: Lipid and Metabolism, Immunology
Application flow cytometry / FACS analysis, flow cytometry / FACS analysis Use 20 ul of reagent per 100 ul of whole blood. , flow cytometry / FACS analysis
Background Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Label:
FITC
Buffer System:
15mM Sodium Azide
Specificity
Specificity:
This antibody recognizes a common epitope on the beta chain of human HLA DR and HLA DP., The HL-38 recognizes common epitope on beta-chain of human HLA-DR and HLA-DP. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages).
Species:
Cross-reacts with Human and Pig.Not yet tested in other species.

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