NB500-447 HLA Class II DR + DP antibody

See related secondary antibodies

Search for all "HLA Class II DR + DP"

0.1 mg / €340.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human HLA Class II DR + DP MEM-136

Product Description for HLA Class II DR + DP

Mouse anti Human HLA Class II DR + DP MEM-136.
Presentation: Aff - Purified
Product is tested for Immunoprecipitation, Western blot / Immunoblot, Flow Cytometry.

Properties for HLA Class II DR + DP

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms DP, HLA class II histocompatibility antigen DR, HLA-DP, HLA-DR, MHC class II antigen DR, W4
Presentation Aff - Purified
Reactivity Hu
Applications F, IP, WB
Clonality Monoclonal
Clone MEM-136
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
PHA-activated peripheral blood lymphocytes.
Add. information Research Areas: Immunology, Lipid and Metabolism
Application flow cytometry / FACS analysis, immunoprecipitation, Western Blot, FACS: Use at an assay dependant concentration. IP: Use at an assay dependant concentration. WB: Use at an assay dependant concentration. Use under non-reducing conditions. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user., flow cytometry / FACS analysis, immunoprecipitation, Western Blot
Background Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Affinity purified
Buffer System:
15mM Sodium Azide
Purity:
Affinity purified
State:
Aff - Purified
Specificity
Specificity:
Common epitope on b-chain of human HLA-DR and HLA-DP. Reacts with alpha-beta dimer as well as with dissociated beta subunit.
Species:
Human

Accessory Products

  • LinkedIn