AM32405SU-N HLA Class II DRw52 antibody

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1 ml / €220.00
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Mouse anti Chimpanzee, Human, Macaque, Gorilla HLA Class II DRw52 7.3.19.1

AM32405SU-N

Product Description for HLA Class II DRw52

Mouse anti Chimpanzee, Human, Macaque, Gorilla HLA Class II DRw52 7.3.19.1.
Presentation: Ascites
Product is tested for Functional assay, Microcytotoxicity, Immunocytochemistry/Immunofluorescence.

Properties for HLA Class II DRw52

Product Category Primary Antibodies
Quantity 1 ml
Synonyms HLA class II histocompatibility antigen DR, HLA-DR, MHC class II antigen DR
Presentation Ascites
Reactivity Chimp, Gorilla, Hu, Macaque
Applications FN, ICC/IF, MC
Clonality Monoclonal
Clone 7.3.19.1
Host Mouse
Isotype IgG2b
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Application The antibody is useful for HLA-DR typing and biochemical characterization of the DR52w positive molecules and Functional Studies. 
Immunofluorescence.
Microcytotoxicity
Recommended Dilutions: 1/10, preferably in PBS with 1% BSA and 0.01% Sodium Azide.
General Readings
  1. Koning, F., et al., 1984, Human Immunology, 9, 221.
  2. Koning, F., et al., 1985, Disease Markers 2, 75.
  3. Bontrop, R.E., et al., 1984, Histocompatibility testing, 526.
  4. Ottenhoff, T.H.M., et al., 1985, Human Immunology, 13, 117.
  5. Bontrop, R.E., et al., 1990, J. Exp. Med. 172, 53.
  6. Verreck, F.A.W., et al., 1993, Eur. J. Immunol. 23, 1346.
Storage Store the antibody undilute at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Buffer System:
PBS
Preservatives:
0.02% Sodium Azide
Stabilizers:
0.1% BSA
State:
Liquid diluted Ascites
Ascites
Species Reactivity
Species reactivity (tested):
Human, Chimpanzee, Gorilla, Macaque.
Specificity
Specificity:
The antibody clone 7.3.19.1 reacts with a polymorphic determinant on HLA-DR molecules which is associated with DR3, DR5, and DRw6 (DRw52-like). It does not react with DRw8.
The antibody reacts with part of the HLA-D molecules (29+34 kD). The determinant is strongly expressed on DR3 positive cells and more weakly on DR5 and DRw6 positive cells.

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