AP52054PU-N HLA-DQA1 (N-term) antibody

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0.4 ml / €370.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human HLA-DQA1


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  • AP52054PU-N
  • AP52054PU-N

Product Description for HLA-DQA1

Rabbit anti Human HLA-DQA1.
Properties: (N-term)
Presentation: Aff - Purified
Product is tested for Flow Cytometry, Western blot / Immunoblot.

Properties for HLA-DQA1

Product Category Primary Antibodies
Quantity 0.4 ml
Synonyms DQ alpha 1 chain, HLA class II histocompatibility antigen
Presentation Aff - Purified
Reactivity Hu
Applications F, WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human HLA-DQA1
Property N-term
Add. information Molecular Weight: 27805 Da

ELISA: 1/1000.
Western Blot: 1/100-1/500.
Flow Cytometry: 1/10-1/50.

Background HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
Concentration lot specific
General Readings Donaldson, P.T., et al. J. Hepatol. 53(6):1049-1053(2010)
Noble, J.A., et al. Diabetes 59(11):2972-2979(2010)
Ferreira, R.C., et al. Nat. Genet. 42(9):777-780(2010)
Ovsyannikova, I.G., et al. PLoS ONE 5 (7), E11806 (2010)
Xun, Y.H., et al. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 23(6):430-433(2009)

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Protein A column, followed by peptide affinity purification
Buffer System:
PBS containing 0.09% (W/V) Sodium Azide as preservative
Liquid purified Ig fraction
Aff - Purified
This antibody recognizes Human HLA-DQA1 (N-term).

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