AM26128PU-N HLA II antibody

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0.2 mg / €280.00
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Quick Overview

Mouse anti Human HLA II HKB1

Product Description for HLA II

Mouse anti Human HLA II HKB1.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Flow Cytometry.

Properties for HLA II

Product Category Primary Antibodies
Quantity 0.2 mg
Synonyms HLA ll, human leukocyte antigen class ll
Presentation Aff - Purified
Reactivity Hu
Applications C, F
Clonality Monoclonal
Clone HKB1
Host Mouse
Isotype IgM
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
REH cells, a Human B cell precursor leukemia cell line.
Remarks:
Antigen: HLA II.
Epitope: has not been further characterized.
Application Immunohistochemistry on Frozen Sections: 1 µg/ml (1/400).
Has been described to work in FACS.
Background The genes of the class II combine to form heterodimeric (αβ) protein receptors that are typically expressed on the surface of antigen presenting cells (APCs): dendritic cells B-cells and macrophages. HLA class II is presented on acticvated T-cells. HLA class II molecules present exogenously derived antigen to the T cell receptor (TCR) on CD4+ T lymphocytes.
Concentration 0.4 mg/ml
General Readings
  1. Barclay, Brown et al.,The Leukocyte Antigen FactsBook, 2nd edition, Harcourt Brace & Company, London, (1997).
Storage Prior to reconstitution store at 2-8°C.
Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography
Buffer System:
Stock solution contains PBS, pH 7.2 with 5 mg/ml BSA as a stabilizer and 0.09% Sodium Azide as preservative.
State:
Lyophilized purified Ig fraction
Aff - Purified
Reconstitution:
Restore by adding 0.5ml distilled water.
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody recognizes all HLA class II antigens, the 3 major (HLA-DP, -DQ and -DR) and 2 minor Major Histocompatibility Complex MHC class II proteins (HLA-DM and -DO).

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