AP32443SU-N Homocysteine antibody

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Rabbit anti Rat Homocysteine


Product Description for Homocysteine

Rabbit anti Rat Homocysteine.
Presentation: Serum
Product is tested for Enzyme Immunoassay.

Properties for Homocysteine

Product Category Primary Antibodies
Quantity 0.1 ml
Presentation Serum
Reactivity Rt
Applications E
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Application ELISA: 1/1,000-1/5,000. 
The antibody may also work for Western blot and Immunohistochemistry (Use 1/500-1/2,500 as a trial dilution).
Background Homocysteine a sulphur containing amino acid, is formed by the transmethylation of methionine, an essential amino acid. Homocysteine may be irreversibly metabolised to cystathionine by cystathionine synthetase. This reaction uses pyridoxal phosphate (Vitamin B6) as a co-enzyme (see figure). The enzyme cystathionine synthetase is deficient in homocysteinuria, a rare genetic disease associated with high blood levels of homocysteine and the development of premature atherosclerosis. This and the association of other rare enzyme deficiencies with homocysteinemia and premature atherosclerosis led McCully to formulate the homocysteine hypothesis of atherosclerosis (McCully KS, The homocysteine theory of atherosclerosis. Atherosclerosis. 1976; 20: 23-27).

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

0.05% Sodium Azide
Liquid Serum
Species Reactivity
Species reactivity (tested):
This antibody recognizes Homocysteine.
The cross-reactivities were determined using an ELISA test by competition experiments with the following compounds:
Compound: Cross-reactivity ratio
Homocysteine-G-BSA: 1
Cysteine-G-BSA: 1/450
Homocysteic acid-G-BSA: 1/> 100,000.G=Glutaraldehyde, BSA=Bovine Serum Albumin.

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