discontinued

bs-0928R HP1 pTyr24 antibody

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0.1 ml / €250.00

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Rabbit anti Drosophila HP1

bs-0928R

Product Description for HP1

Rabbit anti Drosophila HP1.
Properties: pTyr24
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for HP1

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms CG8409, HP1, Heterochromatin protein 1, Non-histone chromosomal protein C1A9 antigen
Presentation Purified
Reactivity Dros
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P05205
Immunogen:
KLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr24.
GeneID:
34119
Property pTyr24
Application WB(1:100-1000)
IHC-P(1:100-500)
IF(IHC-P)(1:50-200)
Background HP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are requiredfor binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.
Storage Store at -20°C for 12 months.
Format
Purification:
Purified by Protein A.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
State:
Purified

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