AP33100PU-N HPV11 E6 Protein (N-term) antibody

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Goat anti Human HPV11 E6 Protein

Product Description for HPV11 E6 Protein

Goat anti Human HPV11 E6 Protein.
Properties: (N-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for HPV11 E6 Protein

Product Category Primary Antibodies
Quantity 0.6 mg
Synonyms Human Papilloma Virus type 11 Early Protein E6
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Goat
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
Purified recombinant peptide derived from within residues 65 aa to N-terminal of HPV11 E6 produced in E. coli.
Property N-term
Application Western blot: 1/500-1/2,000.
Background E6 is one primary oncoprotein of high risk HPV types expressed early in the HPV life cycle. After the host cell is infected viral early promoter is activated and a polycistronic primary RNA containing all six early ORFs is transcribed. This polycistronic RNA then undergoes active RNA splicing to generate multiple isoforms of mRNAs. One of the spliced isoform RNAs, E6, serves as an E7 mRNA to translate E7 protein. HPV genome integrate into host genome by disruption of E2 ORF, preventing E2 repression on E6 and E7. Thus, viral genome integration into host DNA genome increases E6 expression. The E6 protein inactivates the tumour suppressor protein, p53 and promote cellular proliferation and the chance of malignancy.
Concentration 3.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Epitope Affinity Chromatography
Buffer System:
0.05% Sodium Azide
20% Glycerol
Liquid purified IgG fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
This antibody reacts against Human papilloma viruses type 11 (HPV11).
Detects HPV11 E6 recombinant fusion proteins MBP-E6 and GFP-E6 expressed in transfected mammalian cells.

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