NB100-2766 HPV16 E1 + E4 Protein antibody

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Mouse anti Virus HPV16 E1 + E4 Protein TVG 402


Product Description for HPV16 E1 + E4 Protein

Mouse anti Virus HPV16 E1 + E4 Protein TVG 402.
Presentation: Purified
Product is tested for Frozen Sections, Enzyme Immunoassay, Western blot / Immunoblot, Paraffin Sections.

Properties for HPV16 E1 + E4 Protein

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms HPV16 E1 Protein, HPV16 E4 Protein, Human Papilloma Virus type 16
Presentation Purified
Reactivity Vi
Applications C, E, P, WB
Clonality Monoclonal
Clone TVG 402
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Fusion protein: PWAPKK, corresponding to amino acids 36-41 of HPV16 E1+E4. Antigen for hybridoma production was expressed as a b galactosidase fusion protein using the pEX expression system and was consequently cleaved to release the E1/E4 polypeptide.
Isotype control AM03095PU-N
Add. information Research Areas: Immunology
Application ELISA, immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot, ELISA, Western Blot, Immunohistochemistry Paraffin and Frozen Predicted molecular weight 10 kDa. , ELISA assay dependent , immunohistochemistry assay dependent, Western Blot assay dependent, Immunohistochemistry-Paraffin assay dependent, Immunohistochemistry-Frozen assay dependent
Background HPV16 is an ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins. HPV16, in comparison to HPV types 6 and 11, is more often associated with malignant genital cancers in humans. This antibody is of value in monitoring the progress of HPV infection from benign lesions to invasive cancer.
Concentration 1.2 mg/ml
General Readings This product has been used in:Doorbar J et al. The E1E4 protein of human papillomavirus type 16 associates with a putative RNA helicase through sequences in its C terminus. J Virol 74:10081-95 (2000). PubMed PMID: 11024137
Doorbar J et al. Epitope-mapped monoclonal antibodies against the HPV16E1--E4 protein. Virology 187:353-9 (1992). PubMed PMID: 1371027
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
IgG purified
Buffer System:
No Preservative
IgG purified
Amino acids 36-41., Recognises the human papilloma virus type 16 protein.

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