AM50290PU-T Human Kappa Light Chain antibody

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20 µg / €160.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human Human Kappa Light Chain KLC709

Product Description for Human Kappa Light Chain

Mouse anti Human Human Kappa Light Chain KLC709.
Presentation: Purified
Product is tested for Frozen Sections, Flow Cytometry.

Properties for Human Kappa Light Chain

Product Category Primary Antibodies
Quantity 20 µg
Synonyms HCAK1, IGKC, Ig Kappa Chain C Region, Immunoglobulin KM
Presentation Purified
Reactivity Hu
Applications C, F
Clonality Monoclonal
Clone KLC709
Host Mouse
Isotype IgG1
Molecular weight ~22.5kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
Recombinant human Ig kappa chain.
Application ELISA: Use Antibody without BSA for Coating.
Flow Cytometry:
 0.5-1 μg/106 cells.
Immunohistochemistry on Frozen Sections: 0.5-1 μg/ml for 30 min at RT.
Positive Control: 293T, Raji or hPBL cells, Tonsil or Spleen.
Concentration 0.2 mg/ml
General Readings
  1. Kiyotaki M, Cooper MD, Bertoli LF, Kearney JF, Kubagawa H. Monoclonal anti-Id antibodies react with varying proportions of human B lineage cells. J Immunol. 1987 Jun 15;138(12):4150-8. PubMed PMID: 3495581.
  2. Nakamura T, Kubagawa H, Cooper MD. Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies. Proc Natl Acad Sci U S A. 1992 Sep 15;89(18):8522-6. PubMed PMID: 1382292. (Free PMC Article available)
Storage Store undiluted at 2-8°C.
Shelf life: one year from despatch.
Protein A/G Chromatography
Buffer System:
10mM PBS
0.05% Sodium Azide
0.05% BSA
Liquid purified IgG fraction from Bioreactor Concentrate
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Cellular Localization: Cell Surface, cytoplasmic and secreted.

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