discontinued

GTX23187 Hypoxia-inducible factor 1 alpha antibody

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0.5 ml / €340.00

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Mouse anti Human Hypoxia-inducible factor 1 alpha OZ15

GTX23187

Product Description for Hypoxia-inducible factor 1 alpha

Mouse anti Human Hypoxia-inducible factor 1 alpha OZ15.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections.

Properties for Hypoxia-inducible factor 1 alpha

Product Category Primary Antibodies
Quantity 0.5 ml
Presentation Purified
Reactivity Hu
Applications ICC/IF, P
Clonality Monoclonal
Clone OZ15
Host Mouse
Isotype IgG1
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide, corresponding to amino acids 530-826 of Human HIF 1 alpha.
Isotype control AM03095PU-N, SM10P (for use in human samples)
Application GSA, IF
Background HIF-1 (hypoxia-inducible factor 1) is a heterodimer consisting of an alpha and a beta subunit, both belonging to the basic helix loop helix Per-aryl hydrocarbon receptor nuclear translocator Sim (PAS) family of transcription factors. HIF-1 is a key component of a widely operative transcriptional response activated by hypoxia, cobaltous ions, and iron chelation. HIF-1 activates transcription of hypoxia-inducible genes, including those encoding: erythropoietin, vascular endothelial growth (VEGF), heme oxygenase-1, inducible nitric oxide synthase, and the glycolytic enzymes aldolase A, enolase 1, lactate dehydrogenase A, phosphofructokinase I, and phosphoglycerate kinase 1. The C-terminal of HIF-1 alpha binds to p300. p300/CBP-HIF complexes participate in the induction of hypoxia-responsive genes, including VEGF.
Concentration 0.2 mg/ml
Storage Keep as concentrated solution, aliquot and store at 4
Format
Purification:
Protein G purified
Buffer System:
Preservative: 0.09% Sodium Azide; Constituents: 0.2% BSA, 10mM PBS. pH 7.4
Purity:
Protein G purified
State:
Liquid
Purified
Specificity
Specificity:
Human - Not yet tested in other species

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