TA590042 IFNAR1 antibody

Rabbit Polyclonal IFNAR1 Antibody

See related secondary antibodies

Search for all "IFNAR1"

0.1 mg / €409.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human IFNAR1

Product Description for IFNAR1

Rabbit anti Human IFNAR1.
Presentation: Purified
Product is tested for Enzyme Immunoassay.

Properties for IFNAR1

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, IFN-R-1, IFN-alpha Receptor alpha, IFN-alpha/beta receptor 1, Interferon-alpha/beta receptor alpha chain, Type I interferon receptor 1
Presentation Purified
Reactivity Hu
Applications E
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P17181
Immunogen:
DNA immunization. This antibody is specific for the Middle Region of the target protein.
GeneID:
3454
Application ELISA: 1:100-1:2000
Background Interferon alpha receptor 1 (IFN-alpha R1) is a class II cytokine receptor which belongs to type I human interferons (IFNs) family. IFNs plays a role in antiviral, antiproliferative, immunomodulatory, antitumor, and antiparasitic activities by inducing transcription of IFN-stimuated genes (ISGs) through activation of the Jak-STAT pathway. Specifically, IFN- ? R1 is a 135-kda sigl transducing subunit of the IFN alpha/beta receptor complex (IFN-alpha R) (1). IFN-alpha R1 is phospholyated through PTK- and PKC-mediated phosphorylation, which initiates docking of STAT proteins to IFNs. This leads to activation of STAT proteins by PTK-mediated phosphorylation. The mechanism behind the amplification of IFN-alpha R complex mediated transmembrane sigling has been linked to tyrosine phosphorylation on IFN-alpha R1 (2).
Format
Purification:
The fragment used for D immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Buffer System:
20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for IFNAR1 (5 products)

Catalog No. Species Pres. Purity   Source  

IFNAR1

IFNAR1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

IFNAR1

IFNAR1 Human Purified
  Abnova Taiwan Corp.

IFNAR1

IFNAR1 Human Purified
  Abnova Taiwan Corp.

IFNAR1

IFNAR1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

IFNAR1

IFNAR1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for IFNAR1 (1 products)

Catalog No. Species Pres. Purity   Source  

IFNAR1 293T Cell Transient Overexpression Lysate(Denatured)

IFNAR1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.
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