discontinued

NB300-358 IKK1-gamma antibody

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0.05 mg / €410.00

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Chicken anti Human, Mouse, Rat IKK1-gamma

NB300-358

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  • NB300-358

Product Description for IKK1-gamma

Chicken anti Human, Mouse, Rat IKK1-gamma.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for IKK1-gamma

Product Category Primary Antibodies
Quantity 0.05 mg
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Chicken
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Amino acids 1-64 of IKK gamma.
Add. information Research Areas: Immunology
Application Western Blot, WB: Use at a dilution of 1/2000. Predicted molecular weight: 47 kDa. Tissue or cell immunostaining: Use at a starting dilution of 1/200. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user., Western Blot
Background Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
Concentration 1 mg/ml
General Readings General / background references:May MJ et al. Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex. Science 289:1550-4 (2000). PubMed PMID: 10968790
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Immunogen affinity purified
Buffer System:
No Preservative
Purity:
Immunogen affinity purified
State:
Aff - Purified
Specificity
Specificity:
IKK1 gamma
Species:
Human, Mouse, Rat

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