NB100-78226 IL-12 (Interleukin-12) antibody

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0.3 ml / €350.00

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Mouse anti Human IL-12 (Interleukin-12) C8.6


Product Description for IL-12 (Interleukin-12)

Mouse anti Human IL-12 (Interleukin-12) C8.6.
Presentation: Biotin
Product is tested for Enzyme Immunoassay.

Properties for IL-12 (Interleukin-12)

Product Category Primary Antibodies
Quantity 0.3 ml
Synonyms CLMF, Cytotoxic lymphocyte maturation factor, IL12, NK cell stimulatory factor, NKSF
Presentation Biotin
Reactivity Hu
Applications E
Clonality Monoclonal
Clone C8.6
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

COS-expressed p40 subunit of human IL-12
Background The C8.6 antibody reacts with human IL-12 p40 subunit of the IL-12 p70 heterodimer and IL-23 p40 subunit of the IL-23 p19/p40, as well as p40 monomer and homodimer. The C8.6 antibody has been reported to strongly inhibit different biological activities of IL-12, (e.g., IFN-gamma induction, mitogenic effects on PHA blasts, and enhancement of NK cell-mediated cytotoxicity). The C8.6 antibody can neutralize the bioactivity of natural or recombinant IL-12.
General Readings
  1. Fitzgerald, K., et al., Eds. 2001. The Cytokine FactsBook. Academic Press, San Diego. 2. Quesniaux, V. 1992. Research Immunol. 143:385. 3. Trinchieri, G., et al., 1992 Prog. Growth Factor Res. 4:355.
Storage Store at 4C. Do not freeze. Do not freeze.
Immunogen affinity purified
Buffer System:
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% BSA (origin USA).
Immunogen affinity purified
Human, IL-12/IL-23 p40 subunit (monomer, homodimer and heterodimer IL-12 p35/p40 or IL-23 p19/p40).

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