NB100-66214 IL-21 RECEPTOR antibody

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Rabbit anti Human IL-21 RECEPTOR

Product Description for IL-21 RECEPTOR

Rabbit anti Human IL-21 RECEPTOR.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for IL-21 RECEPTOR

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Synthetic peptide CPDLVCYTDYLQT corresponding to amino acids 20-32 of human IL-21 receptor.
Add. information Research Areas: Immunology
Application Western Blot, Western Blot, Western Blot 1ug/ml
Background The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.
Concentration 0.5 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Affinity purified
Buffer System:
0.02% Sodium Azide
Affinity purified
Aff - Purified
Recognizes an epitope within the N-terminal region of human interleukin -21 receptor. The detects a band of approximately 60kD in western blot analysis of human raji cells.

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