NB100-55840 IL-22R (CT) antibody

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0.1 mg / €400.00

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Rabbit anti Human IL-22R (CT)


Product Description for IL-22R (CT)

Rabbit anti Human IL-22R (CT).
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for IL-22R (CT)

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Human IL-22R (CT) peptide.
Background A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified. The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family (3,4). IL-22R forms a complex with IL-10 receptor b chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-a 2 (IL-22RA2), was identified very recently. IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.
Storage Store at 4C. Do not freeze.
Peptide Affinity Purified
Buffer System:
PBS containing 0.02% sodium azide.
Peptide Affinity Purified
Aff - Purified
Human Not yet tested in other species.

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