NBP1-75493 Influenza A Hemagglutinin antibody

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0.1 mg / €440.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Virus Influenza A 1E6A7

NBP1-75493

Product Description for Influenza A

Mouse anti Virus Influenza A 1E6A7.
Properties: Hemagglutinin
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Influenza A

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Vi
Applications E, WB
Clonality Monoclonal
Clone 1E6A7
Host Mouse
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
A peptide corresponding to 13 amino acids in the middle of the Hemagglutinin protein.
Property Hemagglutinin
Background Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA (1). Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found (2). These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong (3). The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low (4). HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability (5). While efforts were made to use relatively conserved regions of the viral sequence as the antigen, the influenza virus genome has drifted somewhat from what was first reported. However, this antibody was able to recognize peptides derrived from viruses from Indonesian human patients infected in 2007.
Storage Store at 4C. Do not freeze.
Format
Purification:
Immunogen affinity purified
Buffer System:
Antibody is supplied in PBS containing 0.02% sodium azide.
State:
Aff - Purified

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