AP20604PU-N Interleukin-12 beta / IL12B antibody

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0.1 mg / €350.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human Interleukin-12 beta / IL12B

Product Description for Interleukin-12 beta / IL12B

Rabbit anti Human Interleukin-12 beta / IL12B.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for Interleukin-12 beta / IL12B

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms CLMF p40, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, IL-12B, Interleukin-12B, NK cell stimulatory factor chain 2, NKSF2
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Molecular weight ~ 44 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P29460
GeneID:
3593
Application Western blot: 1/500 - 1/1000.
Background The interleukins (ILs) are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. As new cytokines are molecularly characterized, they are assigned an IL number to maintain a standard nomenclature. ILs are secreted by immune cells that regulate a wide range of immune system functions. IL-12 is secreted by macrophages and human B-lymphoblastoid cells in response to antigenic stimulation. This IL is responsible for the differentiation of naive CD4+ T cells into type 1 helper T cells that produce interferon-gamma (IFN-gamma). It also activates production of tumor necrosis factor alpha (TNFalpha) from T and natural killer (NK) cells, and it inhibits IL-4 mediated suppression of IFN-gamma. IL-12 also has anti-angiogenic activity since the production of IFN-gamma increases the production of inducible protein-10 (IP-10). IL-12 p40 represents a subunit of IL-12 that is induced by several pathogens. IL-12 p70 is a subunit of IL-12 that is controlled through both the p35 and p40 genes in a cell type-specific fashion.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography (> 95% (by SDS-PAGE)
Buffer System:
Phosphate buffered saline (PBS), pH 7.2.
Preservatives:
0.05% sodium azide
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of IL-12B protein.
(region surrounding Val277)
Gene ID 3593

Accessory Products

Proteins and/or Positive Controls

Proteins for Interleukin-12 beta / IL12B (17 products)

Catalog No. Species Pres. Purity   Source  

Interleukin-12 (p80)

Interleukin-12 Human > 95 % pure by SDS-PAGE gel and HPLC analyses High-5 Insect cells
  OriGene Technologies GmbH

Interleukin-12 p80

Interleukin-12 Human > 95 % pure by SDS-PAGE gel and HPLC analyses High-5 Insect cells
  OriGene Technologies GmbH

Interleukin-12 beta / IL12B

Interleukin-12 beta / IL12B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Interleukin-12 beta / IL12B (full length)

Interleukin-12 beta / IL12B Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Interleukin-12 beta / IL12B

Interleukin-12 beta / IL12B Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
CHO cells
10 µg / €239.00
  OriGene Technologies, Inc.

Interleukin-12 beta / IL12B

Interleukin-12 beta / IL12B Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
10 µg / €139.00
  OriGene Technologies, Inc.

Interleukin-12 beta / IL12B (His-tagged)

Interleukin-12 beta / IL12B Human Purified >95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
E. coli
  OriGene Technologies GmbH

Interleukin-12 beta / IL12B (His-tagged)

Interleukin-12 beta / IL12B Human Purified >95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
E. coli
  OriGene Technologies GmbH

Interleukin-12 beta / IL12B (His-tagged)

Interleukin-12 beta / IL12B Human Purified >95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
E. coli
  OriGene Technologies GmbH

Interleukin-12 beta / IL12B (23-328, His-tag)

Interleukin-12 beta / IL12B Human Purified > 90 % by SDS - PAGE
0.25 mg / €940.00
  OriGene Technologies GmbH

Interleukin-12 beta / IL12B (23-328, His-tag)

Interleukin-12 beta / IL12B Human Purified > 90 % by SDS - PAGE
50 µg / €370.00
  OriGene Technologies GmbH

Interleukin-12 beta / IL12B

Interleukin-12 beta / IL12B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Interleukin-12 beta / IL12B

Interleukin-12 beta / IL12B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Interleukin-12 beta / IL12B

Interleukin-12 beta / IL12B Human
  Abnova Taiwan Corp.

Interleukin-12 beta / IL12B

Interleukin-12 beta / IL12B Human
  Abnova Taiwan Corp.

Interleukin-12 beta / IL12B

Interleukin-12 beta / IL12B Human
  Abnova Taiwan Corp.

Interleukin-12 beta / IL12B

Interleukin-12 beta / IL12B Human
  Abnova Taiwan Corp.

Positive controls for Interleukin-12 beta / IL12B (2 products)

Catalog No. Species Pres. Purity   Source  

IL12B Lysate

Western Blot: IL12B Lysate [NBL1-11901] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for IL12B
  Novus Biologicals Inc.

IL12B overexpression lysate

IL12B overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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