NB100-740 Interleukin-22 Receptor (IL-22R) (42-70) antibody

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0.1 mg / €360.00
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Goat anti Human Interleukin-22 Receptor (IL-22R) (42-70)

NB100-740

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  • NB100-740

Product Description for Interleukin-22 Receptor (IL-22R) (42-70)

Goat anti Human Interleukin-22 Receptor (IL-22R) (42-70).
Presentation: Aff - Purified
Product is tested for Frozen Sections, Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Paraffin Sections.

Properties for Interleukin-22 Receptor (IL-22R) (42-70)

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms IL22R
Presentation Aff - Purified
Reactivity Hu
Applications C, E, ICC/IF, P
Clonality Polyclonal
Host Goat
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide: DSGPEGTPDTVYSIEYKTYGERDWVAKK, corresponding to N terminal amino acids 42-70 of Human IL22 Receptor.
Application ELISA, Immunocytochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunohistochemistry-P: Perform heat mediated antigen retrieval via the pressure cooker method (with citrate buffer pH 6 or pH 8) before commencing with IHC staining protocol. See recommended protocol. Immunohistochemistry-Fr: Fix with ice cold acetone. Immunocytochemistry (cytospun cells on slides): Fix with ice cold acetone. The ELISA dilution is a minimum. Optimal dilutions/concentrations should be determined by the end user., ELISA 1/100000, Immunocytochemistry 1/300, Immunohistochemistry-Paraffin , Immunohistochemistry-Frozen , 1/100 -Fr,
Background The receptor for IL22 (also termed CRF29 and IL TIFR1 chain) is a new member of the class II cytokine receptor family. IL22 Receptor forms a complex with IL10 Receptor beta chain and mediates IL22 signaling. IL22 and its receptor activate the JAK/STAT signaling pathway. IL22 Receptor is expressed in normal liver and kidney and their cell lines HepG2 and TK10.
Concentration 2 mg/ml
General Readings Kotenko SV et al. Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta ) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes. J Biol Chem 276:2725-32 (2001). PubMed PMID: 11035029
Xie MH et al. Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J Biol Chem 275:31335-9 (2000). PubMed PMID: 10875937
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Immunogen affinity purified
Buffer System:
Sodium Azide
Purity:
Immunogen affinity purified
State:
Aff - Purified
Specificity
Specificity:
IL22 Receptor
Species:
Human

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