AM31213AF-N Interleukin-23 alpha / IL23A antibody

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0.5 mg / €460.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human Interleukin-23 alpha / IL23A B-Z23

Product Description for Interleukin-23 alpha / IL23A

Mouse anti Human Interleukin-23 alpha / IL23A B-Z23.
Presentation: Azide Free
Product is tested for Paraffin Sections, Functional assay.

Properties for Interleukin-23 alpha / IL23A

Product Category Primary Antibodies
Target Category
Quantity 0.5 mg
Synonyms IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
Presentation Azide Free
Reactivity Hu
Applications FN, P
Clonality Monoclonal
Clone B-Z23
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9NPF7
Immunogen:
Recombinant Human IL-23 (sub-unit p19)
GeneID:
51561
Remarks:
Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells
Application Functional Assays: Neutralises the bioactivity of rhIL-23 on Mouse splenocytes C57BI/6 (measurement of mIL-17 or mIL-22 production). 
Immunohistochemistry on Paraffin Embedded Sections.
Background The p19 shares sequence similarity with IL-6 subfamily members and is distantly related to the p35 subunit of IL-12. It shows no biological activity by itself; instead, it combines with the p40 subunit of IL-12 to form a biologically active, composite cytokine, IL-23. IL-23 shares some in vivo functions with IL-12, including the activation of the transcription factor Stat4. Similar to IL-12, human IL-23 stimulates IFN-g production and proliferation in PHA blast T cells, as well as in CD45RO (memory) T cells. Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death.
Concentration 1.0 mg/ml
General Readings Obregon, C. et al., PLoS One, 2015; 10(4): e0120134
Storage Store the antibody undiluted at 2-8°C.
Shelf life: one year from despatch.
Format
Purification:
Ion Exchange Chromatography
Buffer System:
Phosphate-buffered saline.
Sterile-filtered through 0.22 µm and treated to remove endotoxins.
Carrier and preservative free.
State:
Liquid purfied IgG fraction
Azide Free
Specificity
Specificity:
This antibody recognizes both recombinant and natural IL-23, p19 sub-unit.
Species:
Human.
Gene ID 51561

Accessory Products

Proteins and/or Positive Controls

Proteins for Interleukin-23 alpha / IL23A (8 products)

Catalog No. Species Pres. Purity   Source  

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
10 µg / €139.00
  OriGene Technologies, Inc.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human > 95 %
Preparation: .
Purity Detail: >95%, as determined by Coomassie stained SDS-PAGE.
10 µg / €231.00
  OriGene Technologies, Inc.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human
  Abnova Taiwan Corp.

Interleukin-23 / IL23

Interleukin-23 / IL23 Human > 95 % pure by SDS-PAGE gel and HPLC analyses. Insect cells
  OriGene Technologies GmbH

Interleukin-23 / IL23

Interleukin-23 / IL23 Human > 95 % pure by SDS-PAGE gel and HPLC analyses. Insect cells
  OriGene Technologies GmbH

Positive controls for Interleukin-23 alpha / IL23A (3 products)

Catalog No. Species Pres. Purity   Source  

IL23A 293T Cell Transient Overexpression Lysate(Denatured)

IL23A 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

IL23A overexpression lysate

IL23A overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

IL23 P19 Lysate

Western Blot: IL23 P19 Lysate [NBL1-11943] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for IL23A
  Novus Biologicals Inc.
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