TA306314 Interleukin-23 alpha / IL23A (C-term) antibody

Rabbit Polyclonal IL-23 Antibody

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0.1 mg / €371.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse Interleukin-23 alpha / IL23A

TA306314

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  • TA306314

Product Description for Interleukin-23 alpha / IL23A

Rabbit anti Human, Mouse Interleukin-23 alpha / IL23A.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for Interleukin-23 alpha / IL23A

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
Presentation Aff - Purified
Reactivity Hu, Ms
Applications E, ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9NPF7
Immunogen:
IL-23 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human IL-23. (AP30418CP-N)
GeneID:
51561
Property C-term
Add. information Blocking peptide available: blocking peptide (AP30418CP-N)
Application ELISA.
Western BLot: 2 - 4 μg/ml.
Immunocytochemistry.
Background Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
General Readings
  1. Hunter CA. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. Nat Rev Immunol. 2005 Jul;5(7):521-31. PubMed PMID: 15999093.
  2. Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity. 2000 Nov;13(5):715-25. PubMed PMID: 11114383.
  3. Sheibanie AF, Tadmori I, Jing H, Vassiliou E, Ganea D. Prostaglandin E2 induces IL-23 production in bone marrow-derived dendritic cells. FASEB J. 2004 Aug;18(11):1318-20. Epub 2004 Jun 4. PubMed PMID: 15180965.
  4. Pirhonen J, Matikainen S, Julkunen I. Regulation of virus-induced IL-12 and IL-23 expression in human macrophages. J Immunol. 2002 Nov 15;169(10):5673-8. PubMed PMID: 12421946.
Storage Store the antibody at 2 - 8°C.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography purified via peptide column
Buffer System:
PBS containing 0.02% sodium azide.
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody reacts to IL-23.
Species:
Human, Mouse.

Accessory Products

Proteins and/or Positive Controls

Proteins for Interleukin-23 alpha / IL23A (8 products)

Catalog No. Species Pres. Purity   Source  

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
10 µg / €139.00
  OriGene Technologies, Inc.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human > 95 %
Preparation: .
Purity Detail: >95%, as determined by Coomassie stained SDS-PAGE.
10 µg / €231.00
  OriGene Technologies, Inc.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Interleukin-23 alpha / IL23A

Interleukin-23 alpha / IL23A Human
  Abnova Taiwan Corp.

Interleukin-23 / IL23

Interleukin-23 / IL23 Human > 95 % pure by SDS-PAGE gel and HPLC analyses. Insect cells
  OriGene Technologies GmbH

Interleukin-23 / IL23

Interleukin-23 / IL23 Human > 95 % pure by SDS-PAGE gel and HPLC analyses. Insect cells
  OriGene Technologies GmbH

Positive controls for Interleukin-23 alpha / IL23A (3 products)

Catalog No. Species Pres. Purity   Source  

IL23A 293T Cell Transient Overexpression Lysate(Denatured)

IL23A 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

IL23A overexpression lysate

IL23A overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

IL23 P19 Lysate

Western Blot: IL23 P19 Lysate [NBL1-11943] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for IL23A
  Novus Biologicals Inc.
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