NB100-66217 Interleukin-6 (IL-6) antibody

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Mouse anti Porcine Interleukin-6 (IL-6) 24D12


Product Description for Interleukin-6 (IL-6)

Mouse anti Porcine Interleukin-6 (IL-6) 24D12.
Product is tested for Western blot / Immunoblot.

Properties for Interleukin-6 (IL-6)

Product Category Primary Antibodies
Quantity 0.5 mg
Synonyms BSF-2, BSF2, CDF, HGF, HSF, IFNB2, IL6, Interferon beta-2, Interleukin 6, MGI-2A
Reactivity Por
Applications WB
Clonality Monoclonal
Clone 24D12
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Application Western Blot
Background Interleukin 6 (IL6) is a multifunctional 24 kDa protein originally discovered in the medium of RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNF alpha, NGF, IL17 and downregulated by glucocorticoids IL4, TGF beta. IL6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL6 has also been implicated in regulating adipose mass.
IL6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. It acts upon a variety of cells including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. In addition, IL6 appears to interact with IL2 in the proliferation of T lymphocytes. IL6 potentiates the proliferative effect of IL3 on multipotential hematopoietic progenitors.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Porcine. Not yet tested in other species.

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