NB100-55917 IRAK (CT) antibody

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0.1 mg / €400.00

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Rabbit anti Human, Mouse, Rat IRAK (CT)


Product Description for IRAK (CT)

Rabbit anti Human, Mouse, Rat IRAK (CT).
Presentation: Aff - Purified
Product is tested for Immunoprecipitation, Western blot / Immunoblot.

Properties for IRAK (CT)

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications IP, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Human IRAK (CT) peptide.
Background Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-kB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).
Storage Store at 4C. Do not freeze.
Affinity Purified
Buffer System:
PBS containing 0.02% sodium azide.
Affinity Purified
Aff - Purified
Human, Mouse, Rat Not yet tested in other species.

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