AP55759PU-S IRAK1 pSer376 antibody

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Search for all "IRAK1"

50 µg / €270.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human IRAK1

Product Description for IRAK1

Rabbit anti Human IRAK1.
Properties: pSer376
Presentation: Aff - Purified
Product is tested for Paraffin Sections.

Properties for IRAK1

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms IRAK, IRAK-1, Interleukin-1 receptor-associated kinase 1
Presentation Aff - Purified
Reactivity Hu
Applications P
Clonality Polyclonal
Host Rabbit
Molecular weight 76 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P51617
Immunogen:
Peptide sequence around phosphorylation site of Serine 376(Q-S-S(p)-M-V) derived from Human IRAK1 (KLH-conjugated)
GeneID:
3654
Property pSer376
Application Immunohistochemistry on paraffin sections: 1:50~1:100 .
Background IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.
Concentration 1.0 mg/ml
General Readings
  1. Cao Z, Henzel WJ, Gao X. IRAK: a kinase associated with the interleukin-1 receptor. Science. 1996 Feb 23;271(5252):1128-31. PubMed PMID: 8599092.
  2. Reichwald K, Thiesen J, Wiehe T, Weitzel J, Poustka WA, Rosenthal A, et al. Comparative sequence analysis of the MECP2-locus in human and mouse reveals new transcribed regions. Mamm Genome. 2000 Mar;11(3):182-90. PubMed PMID: 10723722.
  3. Jensen LE, Whitehead AS. IRAK1b, a novel alternative splice variant of interleukin-1 receptor-associated kinase (IRAK), mediates interleukin-1 signaling and has prolonged stability. J Biol Chem. 2001 Aug 3;276(31):29037-44. Epub 2001 Jun 7. PubMed PMID: 11397809.
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography using epitope-specific peptide
Buffer System:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human
Specificity
Specificity:
The antibody detects endogenous levels of IRAK1 only when phosphorylated at serine 376.

Accessory Products

Proteins and/or Positive Controls

Proteins for IRAK1 (9 products)

Catalog No. Species Pres. Purity   Source  

IRAK1 (transcript variant 3)

IRAK1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

IRAK1

IRAK1 Human
  Abnova Taiwan Corp.

IRAK1

IRAK1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

IRAK1

IRAK1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

IRAK1

IRAK1 Human 12.5% SDS-PAGE Stained with Coomassie Blue
  Abnova Taiwan Corp.

IRAK1

IRAK1 Human 12.5% SDS-PAGE Stained with Coomassie Blue
  Abnova Taiwan Corp.

IRAK1

IRAK1 Human
  Abnova Taiwan Corp.

IRAK1

IRAK1 Human
  Abnova Taiwan Corp.

IRAK1

IRAK1 Human
  Abnova Taiwan Corp.

Positive controls for IRAK1 (6 products)

Catalog No. Species Pres. Purity   Source  

IRAK1 293T Cell Transient Overexpression Lysate(Denatured)

IRAK1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

IRAK1 overexpression lysate

IRAK1 overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.

IRAK1 overexpression lysate

IRAK1 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

IRAK1 overexpression lysate

IRAK1 overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.

IRAK Lysate

Western Blot: IRAK Lysate [NBL1-12025] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for IRAK1
  Novus Biologicals Inc.

IRAK Lysate

Western Blot: IRAK Lysate [NBL1-12026] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for IRAK1
  Novus Biologicals Inc.
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