AP52139PU-N Islet cell autoantigen 1 / ICA1 (N-term) antibody

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0.4 ml / €370.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human Islet cell autoantigen 1 / ICA1

Product Description for Islet cell autoantigen 1 / ICA1

Rabbit anti Human Islet cell autoantigen 1 / ICA1.
Properties: (N-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for Islet cell autoantigen 1 / ICA1

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms 69 kDa islet cell autoantigen, ICA69, ICAp69, Islet cell autoantigen p69
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q05084
Immunogen:
KLH conjugated synthetic peptide between 83-111 amino acids from the N-terminal region of human Islet cell autoantigen 1 / ICA1
GeneID:
3382
Property N-term
Add. information Molecular Weight: 54645 Da
Application ELISA: 1/1000. 
Western Blot: 1/100-1/500.
Background
This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Concentration lot specific
General Readings Jin, Y., et al. Nat. Genet. 42(7):576-578(2010)
Rose, J. Phd, et al. Mol. Med. (2010) In press
Buffa, L., et al. Eur. J. Cell Biol. 87(4):197-209(2008)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)
Gordon, T.P., et al. Lupus 13(6):483-484(2004)
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Protein A column, followed by peptide affinity purification
Buffer System:
PBS containing 0.09% (W/V) Sodium Azide as preservative
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody recognizes Human Islet cell autoantigen 1 / ICA1 (N-term).
Gene ID 3382

Accessory Products

Proteins and/or Positive Controls

Proteins for Islet cell autoantigen 1 / ICA1 (4 products)

Catalog No. Species Pres. Purity   Source  

Islet cell autoantigen 1 / ICA1 (transcript variant 2)

Islet cell autoantigen 1 / ICA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Islet cell autoantigen 1 / ICA1

Islet cell autoantigen 1 / ICA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Islet cell autoantigen 1 / ICA1

Islet cell autoantigen 1 / ICA1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Islet cell autoantigen 1 / ICA1

Islet cell autoantigen 1 / ICA1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for Islet cell autoantigen 1 / ICA1 (2 products)

Catalog No. Species Pres. Purity   Source  

ICA1 Lysate

Western Blot: ICA1 Lysate [NBL1-11801] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for ICA1
  Novus Biologicals Inc.

ICA1 Lysate

Western Blot: ICA1 Lysate [NBL1-11802] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for ICA1
  Novus Biologicals Inc.
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