TA500610 Isocitrate dehydrogenase / IDH antibody

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0.1 ml / €325.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti Human Isocitrate dehydrogenase / IDH OTI2H9

TA500610

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Product Description for Isocitrate dehydrogenase / IDH

Mouse anti Human Isocitrate dehydrogenase / IDH OTI2H9.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Properties for Isocitrate dehydrogenase / IDH

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms Cytosolic NADP-isocitrate dehydrogenase, ICDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, PICD, cytoplasmic Isocitrate dehydrogenase [NADP]
Presentation Purified
Reactivity Hu
Applications ICC/IF, P, WB
Clonality Monoclonal
Clone OTI2H9
Host Mouse
Isotype IgG1
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
O75874
Immunogen:
Full-length protein expressed in 293T cell transfected with human IDH1 expression vector.
GeneID:
3417
Application WB 1:2000
IHC 1:50
IF 1:100
Background Isocitrate dehydrogeses catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes D(+) as the electron acceptor and the other DP(+). Five isocitrate dehydrogeses have been reported: three D(+)-dependent isocitrate dehydrogeses, which localize to the mitochondrial matrix, and two DP(+)-dependent isocitrate dehydrogeses, one of which is mitochondrial and the other predomintly cytosolic. Each DP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the DP(+)-dependent isocitrate dehydrogese found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting sigl sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of DPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, mely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic DPH production.
Product Citations
Originator or purchased from resellers:
  1. Elhammali A, Ippolito JE, Collins L, Crowley J, Marasa J, Piwnica-Worms D. A high-throughput fluorimetric assay for 2-hydroxyglutarate identifies Zaprinast as a glutaminase inhibitor. Cancer Discov. 2014 Jul;4(7):828-39. doi: 10.1158/2159-8290.CD-13-0572. Epub 2014 Apr 16. PubMed PMID: 24740997. (Free PMC Article available)
Format
Purification:
Purified from mouse ascites fluids by affinity chromatography
Buffer System:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for Isocitrate dehydrogenase / IDH (24 products)

Catalog No. Species Pres. Purity   Source  

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH (C-term polyhistidine tag)

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH (C-term DDK tag)

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH (C-term DDK tag)

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH (C-term DDK tag)

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH (C-term DDK tag)

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH (C-term DDK tag)

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Isocitrate dehydrogenase / IDH (1-414, His-tag)

Isocitrate dehydrogenase / IDH Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Isocitrate dehydrogenase / IDH (1-414, His-tag)

Isocitrate dehydrogenase / IDH Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Isocitrate dehydrogenase / IDH

Isocitrate dehydrogenase / IDH Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Positive controls for Isocitrate dehydrogenase / IDH (1 products)

Catalog No. Species Pres. Purity   Source  

Isocitrate dehydrogenase Lysate

Western Blot: Isocitrate dehydrogenase Lysate [NBL1-11817] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for IDH1
0.1 mg / €290.00
  Novus Biologicals Inc.
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