discontinued

TA321454 Tyrosine-protein kinase JAK1 antibody

Anti-JAK1 (Phospho-Tyr1022) Rabbit Polyclonal Antibody

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Rabbit anti Human, Mouse, Rat Tyrosine-protein kinase JAK1

TA321454

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  • TA321454

Product Description for Tyrosine-protein kinase JAK1

Rabbit anti Human, Mouse, Rat Tyrosine-protein kinase JAK1.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for Tyrosine-protein kinase JAK1

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms JAK-1, JAK1A, JAK1B, Janus kinase 1
Presentation Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P23458
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 1022 (K-E-Y(p)-Y-T) derived from Human JAK1.
GeneID:
3716
Application WB: 1:500-1000
IHC: 1:50-100
Background Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon receptor complexes. These kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and of a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs.
Format
Purification:
Antigen affinity purification
Buffer System:
PBS pH7.3, 0.05% NaN3, 50% glycerol.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for Tyrosine-protein kinase JAK1 (4 products)

Catalog No. Species Pres. Purity   Source  

Tyrosine-protein kinase JAK1

Tyrosine-protein kinase JAK1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €788.00
  OriGene Technologies, Inc.

Tyrosine-protein kinase JAK1

Tyrosine-protein kinase JAK1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Tyrosine-protein kinase JAK1

Tyrosine-protein kinase JAK1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Tyrosine-protein kinase JAK1

Tyrosine-protein kinase JAK1 Human
  Abnova Taiwan Corp.

Positive controls for Tyrosine-protein kinase JAK1 (2 products)

Catalog No. Species Pres. Purity   Source  

JAK1 Lysate

Western Blot: JAK1 Lysate [NBL1-12093] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for JAK1
  Novus Biologicals Inc.

JAK1 overexpression lysate

JAK1 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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