discontinued

NB100-64189 Kappa Light Chain antibody

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0.9 mg / €350.00

Quick Overview

Goat anti Human Kappa Light Chain

NB100-64189

Product Description for Kappa Light Chain

Goat anti Human Kappa Light Chain.
Presentation: FITC
Product is tested for Flow Cytometry.

Properties for Kappa Light Chain

Product Category Primary Antibodies
Quantity 0.9 mg
Presentation FITC
Reactivity Hu
Applications F
Clonality Polyclonal
Host Goat
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Application flow cytometry / FACS analysis
Background Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers.
Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Label:
FITC
Purification:
Whole Antisera
Purity:
Whole Antisera
Specificity
Species:
Human. Not yet tested in other species.

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