NB100-64704 Kappa Light Chain antibody

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Sheep anti Human Kappa Light Chain


Product Description for Kappa Light Chain

Sheep anti Human Kappa Light Chain.
Presentation: AP
Product is tested for Frozen Sections, Enzyme Immunoassay, Paraffin Sections.

Properties for Kappa Light Chain

Product Category Primary Antibodies
Quantity 1 ml
Presentation AP
Reactivity Hu
Applications C, E, P
Clonality Polyclonal
Host Sheep
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Native, from urine
Application ELISA, Immunohistochemistry-Frozen, Immunohistochemistry-Frozen and ELISA, ELISA 1:100 - 1:1600, Immunohistochemistry-Frozen 1:20 - 1:100
Background Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers. Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.
Concentration 1 mg/ml
Storage Store at -20C. Avoid freeze-thaw cycles.
Alkaline Phosphatase
IgG purified
Buffer System:
No Preservative
IgG purified
Minimal reactivity with related serum proteins including albumin, IgG and free lambda by Ouchterlony on neat serum.

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