TA328969 KCNH7 antibody

Rabbit polyclonal Anti-KV11.3 (erg3)

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0.2 ml / €622.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat KCNH7

TA328969

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  • TA328969

Product Description for KCNH7

Rabbit anti Human, Mouse, Rat KCNH7.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for KCNH7

Product Category Primary Antibodies
Target Category
Quantity 0.2 ml
Synonyms ERG3, Eag-related protein 3, Ether-a-go-go-related gene potassium channel 3, Ether-a-go-go-related protein 3, HERG-3, KCNH7, Potassium voltage-gated channel subfamily H member 7, Voltage-gated potassium channel subunit Kv11.3
Presentation Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
O54852
Immunogen:
Peptide CPEFLDLEKSKLKSKE, corresponding to amino acid residues 1108-1123 of rat Kv11.3. Intracellular, C-terminal part.
GeneID:
170739
Application WB: 1:200-1:2000; IHC: 1:100-1:3000
Background Kv11.3 (erg3) is a member of the ether-a-go-go (EAG) subfamily of voltage-dependent K+ channels. The erg subfamily includes the closely related proteins Kv11.1 (erg1) and Kv11.2 (erg2) that possess the sigture structure of the voltage-dependent K+ channels: six membrane-spanning domains with intracellular N and C termini. As with all voltage-dependent K+ channels the functiol channel is a tetramer composed of four subunits. It has been suggested that the Kv11 subfamily members can form functiol heteromultimers within the subfamily.The current of the Kv11.1 and Kv11.2 channels is that of a strong inward rectifier with slow activating kinetics. The Kv11.3 channel has different biophysical properties: it is a weak inward rectifier that is activated at negative potentials and has rapid activating kinetics. Kv11.3 expression is believed to be concentrated mainly in the brain with the stronger expression detected in the cerebral cortex and hippocampus.
Format
Purification:
Affinity purified on immobilized antigen.
Buffer System:
Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.025% NaN3.
State:
Purified

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